Antibiotics : actions, origins, resistance / by Christopher Walsh
Walsh, Christopher
Antibiotics : actions, origins, resistance / by Christopher Walsh - Washington, D.C. : ASM Press, c2003 - x, 335 p. : ill. (some col.) ; 26 cm.
Includes bibliographical references (p. 297-328) and index.
Antibiotics : initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair : the Quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis : assembly line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics.
1555812546
2002152389
101157389 DNLM
Antibiotics
Drug resistance in microorganisms.
Antibioticos
615/.329
Antibiotics : actions, origins, resistance / by Christopher Walsh - Washington, D.C. : ASM Press, c2003 - x, 335 p. : ill. (some col.) ; 26 cm.
Includes bibliographical references (p. 297-328) and index.
Antibiotics : initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair : the Quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis : assembly line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics.
1555812546
2002152389
101157389 DNLM
Antibiotics
Drug resistance in microorganisms.
Antibioticos
615/.329