Repic, Oljan, 1948-

Principles of process research and chemical development in the pharmaceutical industry / Oljan Repic. - New York [etc.] : John Wiley & Sons, cop. 1998. - xvi, 213 p. ; 24 cm.

"A Wiley-Interscience publication."

Bibliografía: p. 200-201

This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist of: basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.

0-471-16516-6


Química farmaceútica.
Procesos químicos--Control.
Química orgánica.
Industria farmacéutica
Química industrial

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