Principles of process research and chemical development in the pharmaceutical industry / Oljan Repic.

By: Repic, Oljan, 1948-
Material type: TextText; Format: print Publisher: New York [etc.] : John Wiley & Sons, cop. 1998Description: xvi, 213 p. ; 24 cmISBN: 0-471-16516-6Subject(s): Química farmaceútica | Procesos químicos -- Control | Química orgánica | Industria farmacéutica | Química industrial
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547/REP/pri (Browse shelf) Available   Shelving location | Bibliomaps® BIBLIOG. RECOM. 3742496964
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"A Wiley-Interscience publication."

Bibliografía: p. 200-201

This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist of: basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.

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