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The art of drug synthesis / edited by Douglas S. Johnson, Jie Jack Li

Contributor(s): Johnson, Douglas S [] | Li, Jie Jack [].
Material type: materialTypeLabelBook; Format: print Publisher: Hoboken : John Wiley & Sons, 2007Description: XV, 276 p. ; 26 cm.ISBN: 978-0-471-75215-8.Subject(s): Química farmacéutica | Medicamentos -- Diseño
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615.01/ART (Browse shelf) Available   Shelving location | Bibliomaps® PREST. LIBROS 3742454801
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The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis.. Edited by prominent scientists working in drug discovery for Pfizer. Meets the needs of a growing community of researchers in pharmaceutical R&D. Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students. An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed.

Índice: The role of medicinal chemistry in drug discovery. Process research: how much? How soon?. I. Cancer and infectious diseases. II. Cardiovascular and metabolic diseases. III. Central nervous system diseases. Index.

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