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"Organic Synthesis: Strategy and Control" is the long-awaited sequel to Stuart Warren's bestseller "Organic Synthesis: The Disconnection Approach", which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. A comprehensive, practical account of the key concepts involved in synthesising compounds, it takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations; focuses on reactions that really work rather than those with limited application; and, contains extensive, up-to-date references in each chapter. Students and professional chemists familiar with "Organic Synthesis: The Disconnection Approach" will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.

Índice: Preface.A: Introduction: Selectivity.1. Planning Organic Syntheses: Tactics, Strategy, and Control.2. Chemoselectivity.3. Regioselectivity: Controlled Aldol Reactions.4. Stereoselectivity: Stereoselective Aldol Reactions.5. Alternative Strategies for Enone Synthesis.6. Choosing a Strategy : The Synthesis of cyclopentenones.B: Making Carbon-Carbon Bonds.7. The Ortho Strategy for Aromatic Compounds.8. delta-Complexes of Metals.9. Controlling the Michael Reaction.10. Specific Enol Equivalents.11. Extended Enolates.12. Allyl Anions.13. Homoenolates.14. Acyl Anion Equivalents.C: Carbon-Carbon Double Bonds.15. S... Etc.