Índice

Bibliografía: p. 629-632

This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.

Índice: Preface 1. Prostaglandins, Peptidomimetic Compounds, and Retinoids2. Drug Based on a Substituted Benzene Ring 3. Indenes, Naphthalenes and Other Polycyclic Aromatic Compounds 4. Steroids; Part 1: Estranes, Gonanes and Androstanes 5. Steroids; Part 2: Compounds Related to Progesterone and Cortisone 6. Non-steroidal Sex Hormones and Their Antagonists 7. Opioid Anagesics 8. Drugs Based on Five-membered Heterocycles 9. Drugs Based on Six Membered Heterocycles 10. Five-membered Heterocycles Fused to a Benzene Ring 11. Six-membered Heterocycles Fused to a Benzene Ring 12. Seven-membered Heterocycles Fused to Be... Etc.