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Goodman and Gilman's the pharmacological basis of therapeutics / editor Laurence L.Brunton ; associate editors Bruce A.Chabner, Björn C.Knollmann

Contributor(s): Brunton, Laurence L [] | Chabner, Bruce A [] | Knollmann, Björn C [].
Material type: materialTypeLabelBook; Format: print Publisher: New York : McGraw-Hill, 2011Edition: 12th ed.Description: XVI, 2084 p. : il. ; 26 cm + 1 dvd.ISBN: 978-0-07-162442-8.Subject(s): Farmacología | Terapéutica | Quimioterapia
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Enhanced descriptions from Syndetics:

The landmark text in medical pharmacology is now in full color

Includes DVD with image bank

A Doody's Core Title for 2017!

4 STAR DOODY'S REVIEW!
"This 12th edition of the most authoritative book in pharmacology is the best both in content and physical appearance....This edition of Goodman & Gilman's continues to be the most authoritative and widely used resource bridging the discipline of pharmacology with therapeutics. Moreover, readers will find this edition to be substantially improved from past editions in both content and physical appearance."-- Doody's Review Service

The most universally respected and read medical text in all of pharmacology, Goodman & Gilman's The Pharmacological Basis of Therapeutics represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman's careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease.

Enriched by a new full-color presentation and updated to reflect all critical new developments in drug action and drug-disease interaction, the twelfth edition includes more than 440 color illustrations depicting key principles and actions of specific pathways and therapeutic agents. The companion DVD includes all the images and tables in the text along with narrated animations.

Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e is divided into nine sections, covering:

General Principles Neuropharmacology Modulation of Cardiovascular Function Inflammation, Immunomodulation, and Hematopoiesis Endocrine Pharmacology Gastrointestinal Pharmacology Chemotherapy of Infectious Disease Chemotherapy of Neoplastic Diseases Special Systems Pharmacology

More than a textbook, Goodman & Gilman's is a working template for the effective and rational prescribing of drugs in daily practice.

Índice

Bibliografía

The landmark text in medical pharmacology is now in full color. This title includes DVD with image bank. The most universally respected and read medical text in all of pharmacology, "Goodman & Gilman's The Pharmacological Basis of Therapeutics" represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman's careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease. Enriched by a new full-color presentation and updated to reflect all critical new developments in drug action and drug-disease interaction, the twelfth edition includes more than 440 color illustrations depicting key principles and actions of specific pathways and therapeutic agents. The companion DVD includes all the images and tables in the text along with narrated animations. "Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e" is divided into nine sections, covering: General Principles; Neuropharmacology; Modulation of Cardiovascular Function; Inflammation, Immunomodulation, and Hematopoiesis; Endocrine Pharmacology; Gastrointestinal Pharmacology; Chemotherapy of Infectious Disease; Chemotherapy of Neoplastic Diseases; and, Special Systems Pharmacology. More than a textbook, "Goodman & Gilman's" is a working template for the effective and rational prescribing of drugs in daily practice.

Índice: Contributors Consultants to the Editors Preface Preface to the First Edition SECTION I: GENERAL PRINCIPLES 1. Drug Invention and the Pharmaceutical Industry, Suzanne M. Rivera and Alfred Goodman Gilman 2. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination, Iain L. O. Buxton and Leslie Z. Benet 3. Pharmacodynamics: Molecular Mechanisms of Drug Action, Donald K. Blumenthal and James C. Garrison 4. Drug Toxicity and Poisoning, Kevin C. Osterhoudt and Trevor M. Penning 5. Membrane Transporters and Drug Response, Kathleen M. Giacomini and Yuichi Sugiyama 6. Drug Metabol... Etc.

Table of contents provided by Syndetics

  • Contributors
  • Consultants to the Editors
  • Preface
  • Preface to the First Edition
  • Section I General Principles
  • 1 Drug Invention and the Pharmaceutical Industry
  • 2 Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination
  • 3 Pharmacodynamics: Molecular Mechanisms of Drug Action
  • 4 Drug Toxicity and Poisoning
  • 5 Membrane Transporters and Drug Response
  • 6 Drug Metabolism
  • 7 Pharmacogenetics
  • Section II Neuropharmacology
  • 8 Neurotransmission: The Autonomic and Somatic Motor Nervous Systems
  • 9 Muscarinic Receptor Agonists
  • 10 Anticholinesterase Agents
  • 11 Agents Acting at the Neuromuscular Junction and Autonomic Ganglia
  • 12 Adrenergic Agonists and Antagonists
  • 13 5-Hydroxytryptamine (Serotonin) and Dopamine
  • 14 Neurotransmission and the Central Nervous System
  • 15 Drug Therapy of Depression and Anxiety Disorders
  • 16 Pharmacotherapy of Psychosis and Mania
  • 17 Hypnotics and Sedatives
  • 18 Opioids, Analgesia, and Pain Management
  • 19 General Anesthetics and Therapeutic Gases
  • 20 Local Anesthetics
  • 21 Pharmacotherapy of the Epilepsies
  • 22 Treatment of Central Nervous System Degenerative Disorders
  • 23 Ethanol and Methanol
  • 24 Drug Addition
  • Section III Modulation of Cardiovascular Function
  • 25 Regulation of Renal Function and Vascular Volume
  • 26 Renin and Angiotensin
  • 27 Treatment of Myocardial Ischemia and Hypertension
  • 28 Pharmacotherapy of Congestive Heart Failure
  • 29 Anti-Arrhythmic Drugs
  • 30 Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs
  • 31 Drug Therapy for Hypercholesterolemia and Dyslipiedmia
  • Section Iv Inflammation, Immunomodulation, and Hematopoiesis
  • 32 Histamine, Bradykinin, and Their Antagonists
  • 33 Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor
  • 34 Anti-inflammatory, Antipyretic, and Analgesic Agents; Pharmacology of Gout
  • 35 Immunosupressants, Tolerogens, and Immunostimulants
  • 36 Pulmonary Pharmacology
  • 37 Hematopoietic Agents: Growth Factors, Minerals, and Vitamins
  • Section V Hormones and Hormone Antagonists
  • 38 Introduction to Endocrinology: The Hypothalamic-Pituitary Axis
  • 39 Thyroid and Anti-Thyroid Drugs
  • 40 Estrogens and Progestins
  • 41 Androgens
  • 42 ACTH, Adrenal Steroids, and Pharmacology of the Adrenal Cortex
  • 43 Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia
  • 44 Agents Affecting Mineral Ion Homeostatis and Bone Turnover
  • Section VI Drugs Affecting Gastrointestinal Function
  • 45 Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease
  • 46 Treatment of Disorders of Bowel Motility and Water Flux: Anti-Emetics; Agents Used in Biliary and Pancreative Disease
  • 47 Pharmacotherapy of Inflammatory Bowel Disease
  • Section VII Chemotherapy of Microbial Diseases
  • 48 General Principles of Antimicrobial Therapy
  • 49 Chemotherapy of Malaria
  • 50 Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections
  • 51 Chemotherapy of Helminth Infections
  • 52 Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections
  • 53 Penicillins, Cephalosporins, and Other à-Lactam Antibiotics
  • 54 Aminoglycosides
  • 55 Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents
  • 56 Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy
  • 57 Antifungal Agents
  • 58 Antiviral Agents (Nonretroviral), Edward P. Acosta and Charles Flexner
  • 59 Antiretroviral Agents and Treatment of HIV Infection
  • Section VIII Chemotherapy of Neoplastic Diseases
  • 60 General Principles of Cancer Chemotherapy
  • 61 Cytotoxic Agents
  • 62 Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines
  • 63 Natural Products in Cancer Chemotherapy: Hormones and Related Agents
  • Section IX Ophthalmology
  • 64 Ocular Pharmacology
  • 65 Dermatological Pharmacology
  • 66 Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders
  • 67 Environmental Toxicology: Carcinogens and Heavy Metals
  • Appendices
  • I Principles of Prescription Order Writing and Patient Compliance
  • II Design and Optimization of Dosage Regimens: Pharmacokinetic Data
  • Index

Author notes provided by Syndetics

Editor:
Laurence L. Brunton, PhD
Professor of Pharmacology and Medicine
University of California San Diego
School of Medicine
La Jolla, CA

Associate Editors:
Bruce A. Chabner, MD
Clinical Director
MDF Cancer Center
Professor of Medicine
Harvard Medical School
Boston, MA
Bjorn Christian Knollmann, MD, PhD
Associate Professor of Medicine and Pharmacology
Oates Institute for Experimental Therapeutics
Vanderbilt University School of Medicine
Division of Clinical Pharmacology
Nashville, TN

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