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Stem cells & regenerative medicine : from molecular embryology to tissue engineering / Krishnarao Appasani, Raghu K. Appasani, editors ; foreword by Sir John B. Gordon

Contributor(s): Appasani, Krishnarao [] | Appasani, Raghu K [].
Material type: materialTypeLabelBook; Format: print Series: Stem cell biology and regenerative medicine ; 1.Publisher: New York : Humana Press, 2010Description: XXVII, 629 p. : il. ; 24 cm.ISBN: 9781607618591.Other title: Stem cells and regenerative medicine : from molecular embryology to tissue engineering.Subject(s): Células humanas -- Cultivo | Citología | Células madre
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576/STE (Browse shelf) Available   Shelving location | Bibliomaps® BIBLIOG. RECOM. 3744138844


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Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,â€{u096D}bryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.â€{u0528}at new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies." Offers a comprehensive review of the subject matter Chapters are written by leading scientists and researchers in the field Foreword written by renowned scholar, Professor John GurdonINDICE: Section 1: Stem Cell Biology.- Introduction to Stem Cells & Regenerative Medicine.- Embryonic Stem Cells: Discovery, Development, and Current Trends.- Bmi1 in self-renewal and homeostasis of pancreas.- Cancer Stem Cells inSolid Tumors.- Adipose-derived stem cells and skeletal muscle repair.- Regeneration of sensory cells of adult mammalian inner ear.- Stem Cells and Their Use in Skeletal Tissue Repair.- Section 2: Epigenetic and microRNA Regulation inStem Cells.- Epigenetic identity in cancer stem cells.- Function of MicroRNA-145 in Human Embryonic Stem Cell Pluripotency.- Mesenchymal Stem Cells for Liver Regeneration.- Section 3: Stem Cells for Therapeutic Applications.- The Role of Time-Lapse Microscopy in Stem Cell Research and Therapy.- Therapeutic applications of mesenchymal stem/multipotent stromal cells.- Gastrointestinal stem cells.- Lung epithelial stem cells.- Placental Derived Stem Cells, PotentialClinical Applications.- Bone Marrow Cell Therapy for Acute Myocardial Infarction: A Clinical Trial Review.- Stem cell Transplantation to the Heart

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