TY  - BOOK
AU  - Whitehead,John
TI  - Design and analysis of sequential clinical trials
T2  - Statistics in practice
SN  - 0-471-97550-8
PY  - 1997///
CY  - Chichester [etc.]
PB  - John Wiley & Sons
KW  - Diseño experimental
KW  - Análisis secuencial
KW  - Ensayos clínicos
N2  - In sequential clinical trials, data from patients treated at the beginning of a trial can be analyzed while the trial is still in progress and subsequent patients can be recruited. This analysis provides stopping rules whereby the number of patients involved can be limited without affecting the results
ER  -