TY  - BOOK
AU  - Johnson,Douglas S.
AU  - Li,Jie Jack
TI  - The art of drug synthesis
SN  - 978-0-471-75215-8
PY  - 2007///
CY  - Hoboken
PB  - John Wiley & Sons
KW  - Química farmacéutica
KW  - Medicamentos
KW  - Diseño
N1  - Indice analítico; Bibliografía
N2  - The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis.. Edited by prominent scientists working in drug discovery for Pfizer. Meets the needs of a growing community of researchers in pharmaceutical R&D. Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students. An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed; Índice: The role of medicinal chemistry in drug discovery. Process research: how much? How soon?. I. Cancer and infectious diseases. II. Cardiovascular and metabolic diseases. III. Central nervous system diseases. Index
ER  -