TY - BOOK AU - Hudlický,Tomás AU - Reed,Josephine W. TI - The way of synthesis: evolution of design and methods for natural products SN - 9783527320776 (hbk.) PY - 2007/// CY - Weinheim PB - Wiley-VCH KW - Síntesis orgánica N1 - Índice; Bibliografía N2 - This two-coloured textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinary, with personal recollections of the chemists, who synthesized these fascinating compounds.With its attractive layout highlighting key parts and tactics using a second colour, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry. 'I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication' - Victor Snieckus; Índice: Foreword.Preface.Part 1: Introduction.Part 2: Strategy and Tactics.Part 3: Comparative Design: Classics in Terpene Synthesis.Part 34: Comparative Design: Classics in Alkaloid Synthesis.Part 5: Miscellaneous Compounds.Part 6: Outlook.Part 7: Acknowledgments.Part 8: Appendix.Subject Index.Author Index.Index of personal recollection ER -