Indice

Bibliografía: p. 473-521

Bioorganic chemistry is commonly described as the study of chemistry of living systems using the strategies and methodologies traditionally associated with organic chemistry. Recently, this fast moving sub-discipline has witnessed some very exciting results in applying design and synthesis techniques to the most difficult problems in molecular biology. Much of the current work in areas as: protein folding; signal transduction; molecular recognition; monoclonal antibodies; and drug design, is being conducted by bioorganic chemists. Bioorganic Chemistry: Peptides and Proteins is the second of the three text references being prepared (edited) by Sidney Hecht to service the needs of the many graduate students and researchers who have strong interest in this field.

Índice: Preface Contributors 1. Introduction to Peptides and Proteins , Milton J. Axley 2. Chemical Synthesis of Peptides , Victor Hruby and Jean-Philippe Meyer 3. Total Chemical Synthesis of Proteins , Michael C. Fitzgerald and Stephen B.H. Kent 4. Structural Analysis of Proteins , John E. Shively 5. Protein Structure , Charles W. Carter. Jr. 6. Protein Folding , Zhi-Ping Liu, Josep Rizo, and Lila M. Gierasch 7. Nucleic Acid Interactive Protein Domains That Require Zinc , Michael A. Massiah, Paul R. Blake, and Michael F. Summers 8. Understanding the Mechanisms and Rates of Enzyme-Catalyzed Proton Transfer Reactio... Etc.