Bibliografía. - Indice

Human Molecular Biology is an introduction to the molecular basis of health and disease for the new generation of life scientists and medical students. By integrating cutting-edge molecular genetics and biochemistry with the latest clinical information, the book weaves a pattern which unifies biology with syndromes, genetic pathways with developmental phenotypes, and protein function with drug action. From the origins of life to the present day, a narrative is traced through the workings of genomes, cells and organ systems, culminating in linking of laboratory technologies to future research horizons. Lavishly illustrated throughout with two-colour diagrams and full colour clinical pictures, this text brings the complexities and breadth of human molecular biology clearly to life. This seamless account breaks through the boundaries between molecular biology and medicine, and leads the reader on to a new dimension where the biological basis of health and disease is inescapably molecular.

INDICE: 1. Introduction - a disease for every gene? Part I. From Molecular Biology to Human Genetics: 2. Biomolecular evolution; 3. Chromatin and chromosomes; 4. Gene expression; 5. RNA processing and translation; 6. Protein structure and function; Part II. From Molecular Genetics to Human Biochemistry: 7. Nutrition and energy; 8. Membranes and channels; 9. Cell surface receptors; 10. Adhesion molecules and the extracellular matrix; 11. Cytoskeletal and motor proteins; Part III. From Molecular Biochemistry to Human Cell Biology: 12. Signal transduction; 13. Inflammatory cytokines; 14. Hormones and growth factors;... Etc.