Principles of process research and chemical development in the pharmaceutical industry / Oljan Repic.
Tipo de material:
TextoDetalles de publicación: New York [etc.] : John Wiley & Sons, cop. 1998. Descripción: xvi, 213 p. ; 24 cmISBN: 0-471-16516-6Tema(s): Química farmaceútica | Procesos químicos -- Control | Química orgánica | Industria farmacéutica | Química industrialResumen: This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist of: basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.
| Tipo de ítem | Biblioteca de origen | Signatura | URL | Estado | Fecha de vencimiento | Código de barras | Reserva de ítems |
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"A Wiley-Interscience publication."
Bibliografía: p. 200-201
This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist of: basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.
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